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A mixture of purified porcine gangliosides; found in all cells but at particularly high levels in the brain; typically contain stearic acid as the fatty acyl chain; modulate intra- and inter-cell signaling and regulate receptor function; involved in developmental processes; implicated in tumorigenesis
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Complement C3/C3a protein activates the complement system playing a central role in both classical and alternative pathways C3b binds covalently to cell surface carbohydrates or immune aggregates while C3a acts as an inflammatory mediator inducing neutrophil chemoattraction and promoting smooth muscle contraction increased vascular permeability and histamine release The shorter isoform of C3a stimulates B-cells Complement C3/C3a Protein Mouse is the recombinant mouse-derived Complement C3/C3a protein expressed by E coli with tag free
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This gene encodes a member of the S1 or chymotrypsin family of serine peptidases This protease catalyzes the cleavage of factor B the rate-limiting step of the alternative pathway of complement activation This protein also functions as an adipokine a cell signaling protein secreted by adipocytes which regulates insulin secretion in mice Mutations in this gene underlie complement factor D deficiency which is associated with recurrent bacterial meningitis infections in human patients Alternative splicing of this gene results in multiple transcript variants At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease
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The Meso Scale Discovery U-PLEX Human Complement C9 Assay Kit quantifies Complement C9 in human serum plasma urine cell culture supernatants and other samples This electrochemiluminescent immunoassay uses MSD s SULFO-TAG labels and multi-array technology for sensitive detection The kit includes a 96-well plate with capture antibody detection antibody with ruthenium label calibrators and necessary reagents Results are available in 3 5 hours with a dynamic range of 78 - 50 000 pg/mL offering a robust tool for immunology research
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